Invitrogen™ SAA Monoclonal Antibody (Reu86.1)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA140180

Catalog No. 01-676-542

Description

MA1-40180 detects SAA from human and mouse samples. MA1-40180 is raised against human SAA and Helix Pomatia Haemocyanine. It reacts specifically with SAA-1, the major isoform of SAA in plasma. MA1-40180 has been successfully used in immunohistochemistry (frozen and paraffin), western blot, and immunoassay applications. It is recommended that users test the reagent and determine their own optimal dillutions. The MA1-40180 immunogen is human SAA.

The serum amyloid A family comprises a number of differentially expressed apolipoproteins, acute-phase SAA1 and SAA2, the former being the major component in plasma and constitutive SAAs. Although the liver is the primary site of synthesis of both SAA types extrahepatic production has been reported. The in vivo concentrations increase by as much as 1000 fold during inflammation. Several studies have expressed its importance in the diagnosis and monitoring of various diseases. Pathological SAA values are often detected in association with normal CRP concentrations; SAA rises earlier and more sharply than CRP. Recently, a broader view of SAA expression and function has been emerging.

Specifications

• Antigen: SAA
• Classification: Monoclonal
• Concentration: 0.1 mg/mL
• Formulation: PBS with 0.1% BSA and 0.02% sodium azide
• Gene Accession No.: P05366, P0DJI8
• Gene Symbols: Saa, SAA1
• Immunogen: Human SAA.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG1

• Applications: ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
• Clone: Reu86.1
• Conjugate: Unconjugated
• Gene: SAA1
• Gene Alias: amyloid a; Amyloid fibril protein AA; Amyloid protein A; MGC111216; PIG4; SAA; SAA1; Saa-1; Saa2; serum amyloid A; serum amyloid A 1; serum amyloid A 2; serum amyloid A protein; serum amyloid A1; Serum amyloid A1 protein; Serum amyloid A-1 protein; serum amyloid A-like protein; Serum amyloid protein A(2-102); Serum amyloid protein A(2-103); Serum amyloid protein A(2-104); Serum amyloid protein A(3-104); Serum amyloid protein A(4-101); Serum Amyloid-A; TP53I4; tumor protein p53 inducible protein 4
• Host Species: Mouse
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 111345, 20208, 6288
• Content And Storage: 4°C
• Form: Liquid