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Invitrogen™ Saccharomyces cerevisiae ZIP1 Polyclonal Antibody
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Catalog No. PIPA5117585
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100 μL
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PIPA5117585 100 μL
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Catalog No. PIPA5117585 Supplier Invitrogen™ Supplier No. PA5117585
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Description

Rabbit Polyclonal Antibody

This antibody has been tested in direct-ELISA.

ZIP1, also known as ZIRTL (zinc-iron regulated transporter-like), is the first mammalian member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP1 expression is markedly downregulated in a number of cancerous tissues and is thought to function as a tumor suppressor gene in prostate cancer. More recent studies have shown that overexpression of ZIP1 and concomitant increased levels of intracellular zinc in PC-3 cells cause a significant inhibition of NF-kappa-B, leading to down-regulation of the antiapoptotic protein Bcl-2, Bcl-XL, and the apoptosis inhibitor XIAP, reducing the malignant potential of prostate cancer cells in vitro and in vivo.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Saccharomyces cerevisiae ZIP1
Applications Western Blot
Classification Polyclonal
Concentration 2.95 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene ZIP1
Gene Accession No. P31111
Gene Alias CGI-08; CGI-71; IRT1; mZIP1; SLC39A1; solute carrier family 39 (zinc transporter), member 1; solute carrier family 39 (zinc transporter), member 3; solute carrier family 39 member 1; Zinc transporter ZIP1; Zinc-iron-regulated transporter-like; Zip1; ZIP-1; ZIRTL; Zrt- and Irt-like protein 1; Zrt/Irt-like protein 1
Gene Symbols ZIP1
Host Species Rabbit
Immunogen Recombinant Saccharomyces cerevisiae Synaptonemal complex protein ZIP1 protein (1-227aa).
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 851879
Target Species Yeast
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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