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SAHA, Tocris Bioscience™

Catalog Number 465250
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
149647-78-9
C14H20N2O3
264.325
WAEXFXRVDQXREF-UHFFFAOYSA-N
vorinostat, saha, suberoylanilide hydroxamic acid, zolinza, n-hydroxy-n'-phenyloctanediamide, suberanilohydroxamic acid, n1-hydroxy-n8-phenyloctanediamide, saha cpd, vorinostat usan, octanediamide, n-hydroxy-n'-phenyl
5311
CHEBI:45716
N'-hydroxy-N-phenyloctanediamide
C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NO
This item is not returnable. View return policy
149647-78-9
C14H20N2O3
264.325
WAEXFXRVDQXREF-UHFFFAOYSA-N
vorinostat, saha, suberoylanilide hydroxamic acid, zolinza, n-hydroxy-n'-phenyloctanediamide, suberanilohydroxamic acid, n1-hydroxy-n8-phenyloctanediamide, saha cpd, vorinostat usan, octanediamide, n-hydroxy-n'-phenyl
5311
CHEBI:45716
N'-hydroxy-N-phenyloctanediamide
C1=CC=C(C=C1)NC(=O)CCCCCCC(=O)NO

Class I and II HDAC inhibitor

SAHA inhibits Class I and II histone deacetylases (HDACs); induces accumulation of acetylated histones H2A, H2B, H3 and H4 in transformed cultured cells. Suppresses cell growth in a range of cancer cell lines; induces apoptosis in cutaneous T cell lymphoma cells in vitro. Activates autophagy. SAHA increases efficiency of transcription factor-induced reprogramming of mouse embryonic fibroblasts (MEF) to induced pluripotent stem cells (iPSC). Also enhances adeno-associated virus transduction of HeLa cells.
Quantity 50 mg
Formula Weight 264.32
Percent Purity >98%
Chemical Name or Material SAHA
Recommended Storage Store at -20°C
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