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Invitrogen™ SAP18 Polyclonal Antibody
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Catalog No. PIPA578314
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100 μL
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PIPA578314 100 μL
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Catalog No. PIPA578314 Supplier Invitrogen™ Supplier No. PA578314
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Description

Rabbit Polyclonal Antibody

Positive Control: K562, K562 nuclear extract Predicted Reactivity: Mouse (98%), Rat (98%), Zebrafish (90%), Xenopus laevis (87%), Dog (99%), Chicken (99%), Rhesus Monkey (100%), Bovine (99%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

SAP18 is involved in histone acetylation, which plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SAP18
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene SAP18
Gene Accession No. O00422
Gene Alias 18 kDa Sin3-associated polypeptide; 2HOR0202; C530046K05Rik; cell growth inhibiting protein 38; cell growth-inhibiting gene 38 protein; cell growth-inhibiting protein 38; D11Ertd539e; EMegR4; GIG38; histone deacetlyase complex subunit SAP18; histone deacetylase complex subunit SAP18; SAP18; SAP18P; Sin3A associated protein 18; Sin3A associated protein 18kDa; Sin3A-associated protein, 18kDa; Sin3-associated polypeptide 18; sin3-associated polypeptide p18; sin3-associated polypeptide, 18 kDa; sin3-associated polypeptide, 18kDa; sin3-associated polypeptide, p18; Sinbp1
Gene Symbols SAP18
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the center region of human SAP18. The exact sequence is proprietary.
Purification Method Antigen Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10284
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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