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Invitrogen™ Sarcalumenin Monoclonal Antibody (XIIC4)
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Catalog No. MA3932
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100 μL
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MA3932 100 μL
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Catalog No. MA3932 Supplier Invitrogen™ Supplier No. MA3932
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Mouse Monoclonal Antibody

MA3-932 detects sarcalumenin from canine, guinea pig, mouse and rabbit tissues. This antibody specifically detects sarcalumenin and the 53 kDa glycoprotein splice variant. MA3-932 has been successfully used in Western blot. By Western blot, this antibody detects a 53 kDa and a 160 kDa protein representing the glycoprotein and sarcalumenin, respectively, in rabbit skeletal muscle extracts. The MA3-932 antigen is purified rabbit sarcoplasmic reticulum membrane vesicles.

Sarcalumenin is a 160 kDa acidic calcium binding glycoprotein found to reside at the inner membrane of the sarcoplasmic reticulum in a calcium dependent manner. The gene encoding sarcalumenin also encodes an alternate splice variant, a 53 kDa glycoprotein which co-localizes with sarcalumenin. These two proteins are found in the longitudinal sarcoplasmic reticulum and the nonjunctional membranes of the terminal cisternae. They have been observed to co-localize with calcium-ATPase suggesting that they are involved in calcium transport and sequestration.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Sarcalumenin
Applications Western Blot, Immunocytochemistry
Classification Monoclonal
Clone XIIC4
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene SRL
Gene Accession No. P13666, Q7TQ48
Gene Alias 9830004M20Rik; AW108387; Sar; sarcalumenin; sarcolumenin; sarcolumenin precursor; sarcoplasmic reticulum glycoprotein; Srl
Gene Symbols SRL
Host Species Mouse
Immunogen Purified rabbit sarcoplasmic reticulum membrane vesicles.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100009112, 100719273, 106393, 302948, 490030
Target Species Mouse, Rat, Canine, Rabbit, Guinea Pig
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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