Invitrogen™ Sarcalumenin Monoclonal Antibody (XIIC4)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA3932

Catalog No. MA3932

Description

MA3-932 detects sarcalumenin from canine, guinea pig, mouse and rabbit tissues. This antibody specifically detects sarcalumenin and the 53 kDa glycoprotein splice variant. MA3-932 has been successfully used in Western blot. By Western blot, this antibody detects a 53 kDa and a 160 kDa protein representing the glycoprotein and sarcalumenin, respectively, in rabbit skeletal muscle extracts. The MA3-932 antigen is purified rabbit sarcoplasmic reticulum membrane vesicles.

Sarcalumenin is a 160 kDa acidic calcium binding glycoprotein found to reside at the inner membrane of the sarcoplasmic reticulum in a calcium dependent manner. The gene encoding sarcalumenin also encodes an alternate splice variant, a 53 kDa glycoprotein which co-localizes with sarcalumenin. These two proteins are found in the longitudinal sarcoplasmic reticulum and the nonjunctional membranes of the terminal cisternae. They have been observed to co-localize with calcium-ATPase suggesting that they are involved in calcium transport and sequestration.

Specifications

• Antigen: Sarcalumenin
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 0.05% sodium azide
• Gene Accession No.: P13666, Q7TQ48
• Gene Symbols: SRL
• Immunogen: Purified rabbit sarcoplasmic reticulum membrane vesicles.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse, Rat, Canine, Rabbit, Guinea Pig
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot, Immunocytochemistry
• Clone: XIIC4
• Conjugate: Unconjugated
• Gene: SRL
• Gene Alias: 9830004M20Rik; AW108387; Sar; sarcalumenin; sarcolumenin; sarcolumenin precursor; sarcoplasmic reticulum glycoprotein; Srl
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 100009112, 100719273, 106393, 302948, 490030
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid