Invitrogen™ SARS/SARS-CoV-2 Nucleocapsid Monoclonal Antibody (E16C)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA17403

Catalog No. PIMA17403

Description

MA1-7403 is reactive with the NP of SARS-CoV-2 (COVID-19 virus) by ELISA. Negative for human coronaviruses 229E & OC43. ELISA dilution range suggested 1:20- 1:200. The MA1-7403 antibody reacts with SARS Coronavirus nucleoprotein in viral and infected tissue samples. MA1-7403 has been successfully used in ELISA, Western blot and Immunofluorescence applications. The MA1-7403 antibody was raised against a SARS virus nucleoprotein preparation.

SARS-CoV-2 Nucleocapsid Protein is associated with nucleic acid. It is the most abundant protein for coronavirus. Because of the strong immunogenicity of coronavirus Nucleocapsid, it is believed that SARS-CoV-2 Nucleocapsid Protein has potential value for the diagnosis of the virus. The SARS-CoV-2 N protein is an abundant RNA-binding protein critical for viral genome packaging, yet the molecular details that involve this process are poorly understood. N protein contains three dynamic disordered regions that house putative transiently-helical binding motifs. The two folded domains interact minimally such that full-length N protein is a flexible and multivalent RNA-binding protein. SARS-CoV-2 causes illnesses ranging from the common cold to severe diseases.

Specifications

• Antigen: SARS/SARS-CoV-2 Nucleocapsid
• Classification: Monoclonal
• Concentration: 0.1 mg/mL
• Formulation: PBS with 0.1% sodium azide; pH 7.2
• Gene Accession No.: P0DTC9
• Gene Symbols: N
• Immunogen: SARS nucleoprotein preparation.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Virus
• Product Type: Antibody
• Isotype: IgG2b

• Applications: ELISA, Immunohistochemistry, Western Blot
• Clone: E16C
• Conjugate: Unconjugated
• Gene: N
• Gene Alias: COVID19 Nucleocapsid; COVID-19 nucleocapsid; COVID19 Spike nucleocapsid; SARS-CoV-2 N
• Host Species: Mouse
• Purification Method: Protein A
• Regulatory Status: RUO
• Gene ID (Entrez): 43740575
• Content And Storage: 4°C
• Form: Liquid