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Invitrogen™ SARS-CoV-2 Membrane Recombinant Rabbit Monoclonal Antibody (HL1087)
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Catalog No. PIMA546923
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100 μL
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PIMA546923 100 μL
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Catalog No. PIMA546923 Supplier Invitrogen™ Supplier No. MA546923
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Rabbit Recombinant Monoclonal Antibody

Store as concentrated solution. Centrifuge briefly prior to opening vial.

The coronavirus membrane protein (M) is the most abundant viral structural protein and plays a central role in virus assembly and morphogenesis M protein forms a mushroom-shaped dimer, composed of two transmembrane domain-swapped three-helix bundles and two intravirion domains M protein further assembles into higher-order oligomers A highly conserved hinge region is key for conformational changes The M protein dimer is unexpectedly similar to SARS-CoV-2 ORF3a, a viral ion channel The interaction analyses of M protein with nucleocapsid protein (N) and RNA suggest that the M protein mediates the concerted recruitment of these components through the positively charged intravirion domain [PMID: 35931673].
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Specifications

Antigen SARS-CoV-2 Membrane
Applications Western Blot, Immunocytochemistry
Classification Recombinant Monoclonal
Clone HL1087
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene Alias CoV-2; SARS
Host Species Rabbit
Immunogen Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of SARS-CoV-2 (COVID-19) Membrane. The exact sequence is proprietary.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Target Species Virus
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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