Invitrogen™ SARS-CoV-2 Nucleocapsid (A12G, T205I) His-tag Recombinant Protein

Catalog No.	Quantity
PIRP88449	100 μg

Catalog No. PIRP88449 Supplier Invitrogen™ Supplier No. RP88449

Description

Recombinant Protein

It is recommended that the protein be aliquoted for optimal storage. It is recommended that sterile water (500 μL) be added to the vial to prepare a stock solution of 0.2 mg/mL. Concentration is measured by UV. The mutations were identified in the SARS-CoV-2 varient known as B.1.525.

SARS-CoV-2 Nucleocapsid Protein is associated with nucleic acid. It is the most abundant protein for coronavirus. Because of the strong immunogenicity of coronavirus Nucleocapsid, it is believed that SARS-CoV-2 Nucleocapsid Protein has potential value for the diagnosis of the virus. The SARS-CoV-2 N protein is an abundant RNA-binding protein critical for viral genome packaging, yet the molecular details that involve this process are poorly understood. N protein contains three dynamic disordered regions that house putative transiently-helical binding motifs. The two folded domains interact minimally such that full-length N protein is a flexible and multivalent RNA-binding protein. SARS-CoV-2 causes illnesses ranging from the common cold to severe diseases.

Specifications

• Accession Number: P0DTC9
• For Use With (Application): Control, Neutralization
• Format: Lyophilized
• Formulation: PBS with 0.01% mannitol, 5-8% trehalose, 0.01% Tween 80 and no preservative; pH 7.4
• Gene ID (Entrez): 43740575
• Molecular Weight (g/mol): 46.6 kDa
• Name: SARS-CoV-2 Nucleocapsid (A12G, T205I) His-tag
• pH Range: 7.4
• Purification Method: Purified
• Quantity: 100 μg
• Storage Requirements: -20°C, Avoid Freeze/Thaw Cycles
• Regulatory Status: RUO
• Gene Alias: COVID19 Nucleocapsid; COVID-19 nucleocapsid; COVID19 Spike nucleocapsid; SARS-CoV-2 N
• Common Name: SARS-CoV-2 Nucleocapsid
• Gene Symbol: N
• Product Type: Protein
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Protein Tag: His-tag
• Sequence: SARS-CoV-2 nucleocapsid, amino acids Met1-Ala419 (Accesion # YP_009724397.2 with substitutions A12G, T205I) with an N-terminal His-tag
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Expression System: E. coli
• Form: Lyophilized
• Purity or Quality Grade: >95% as determined by SDS-PAGE.