Invitrogen™ SARS-CoV-2 Spike Protein (RBD) (aa319-541), His Tag Recombinant Protein

Catalog No.
PIRP87697	1 mg; Unlabeled

Catalog No. PIRP87697 Supplier Invitrogen™ Supplier No. RP87697

Description

Recombinant Protein

SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) also known as 2019-nCoV (2019 Novel Coronavirus) is a virus that causes illnesses ranging from the common cold symptoms to severe effects including death and respiratory distress. The CoV Spike (S) protein plays the most important roles in viral attachment, fusion and entry, and serves as a target for development of antibodies, entry inhibitors and vaccines. Of note is the Spike protein receptor-binding domain (RBD, S-RBD) in SARS-CoV-2 Spike protein which binds strongly to human and bat angiotensin-converting enzyme 2 (ACE2) receptors. SARS-CoV-2 RBD exhibits significantly higher binding affinity to ACE2 receptor than SARS-CoV RBD in comparison. S1 contains a receptor-binding domain (RBD) that can specifically bind to angiotensin-converting enzyme 2 (ACE2), the receptor on target cells.

Specifications

• For Use With (Application): Control, ELISA, Western Blot
• Formulation: PBS with no preservative; pH 7.4
• Name: SARS-CoV-2 Spike Protein RBD
• Quantity: 1 mg
• Storage Requirements: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Regulatory Status: RUO
• Gene Alias: Coronavirus; COVID; Covid 19; COVID19; COVID-19; SARS; SARS Coronavirus; SARS CoV; SARS CoV2; SARS CoV-2; SARS Spike Protein; SARS-CoV2; SARS-CoV-2
• Conjugate: Unconjugated
• Recombinant: Recombinant
• Expression System: HEK293 cells
• Form: Liquid
• Purity or Quality Grade: >95% by SDS-PAGE