Invitrogen™ SBF1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA588490

Catalog No. PIPA588490

Description

Immunogen sequence: PPYDWELAQG PPEPPEEERS DGGAPQSRRR VVWPCYDSCP RAQPDAISRL LEELQRLETE LGQPAERWKD TWDRVKAAQR LEGRPDGRGT PSSLLVSTAP HHRRSLGVYL QEGPVGSTLS LSLDSDQSSG STTSGSRQAA R; Positive Samples: Raji, Jurkat, Rat brain; Cellular Location: Nucleus.

Probable pseudophosphatase. Lacks several amino acids in the catalytic pocket which renders it catalytically inactive as a phosphatase. The pocket is however sufficiently preserved to bind phosphorylated substrates, and maybe protect them from phosphatases. Inhibits myoblast differentiation in vitro and induces oncogenic transformation in fibroblasts. According to PubMed:20937701, may function as a guanine nucleotide exchange factor (GEF) activating RAB28. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.

Specifications

• Antigen: SBF1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Sbf1
• Gene Alias: CMT4B3; DENN/MADD domain containing 7A; DENND7A; Inactive phosphatidylinositol 3-phosphatase 5; MTMR5; Myotubularin-related protein 5; Sbf1; SET binding factor 1; SET-binding factor 1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 300147, 6305
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.73 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: O95248
• Gene Symbols: Sbf1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1630-1770 of human SBF1 (NP_0029632).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov