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Invitrogen™ SBF1 Polyclonal Antibody
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Catalog No. PIPA588490
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100 μL
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PIPA588490 100 μL
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Catalog No. PIPA588490 Supplier Invitrogen™ Supplier No. PA588490
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: PPYDWELAQG PPEPPEEERS DGGAPQSRRR VVWPCYDSCP RAQPDAISRL LEELQRLETE LGQPAERWKD TWDRVKAAQR LEGRPDGRGT PSSLLVSTAP HHRRSLGVYL QEGPVGSTLS LSLDSDQSSG STTSGSRQAA R; Positive Samples: Raji, Jurkat, Rat brain; Cellular Location: Nucleus.

Probable pseudophosphatase. Lacks several amino acids in the catalytic pocket which renders it catalytically inactive as a phosphatase. The pocket is however sufficiently preserved to bind phosphorylated substrates, and maybe protect them from phosphatases. Inhibits myoblast differentiation in vitro and induces oncogenic transformation in fibroblasts. According to PubMed:20937701, may function as a guanine nucleotide exchange factor (GEF) activating RAB28. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SBF1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 3.46 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Sbf1
Gene Accession No. O95248
Gene Alias CMT4B3; DENN/MADD domain containing 7A; DENND7A; Inactive phosphatidylinositol 3-phosphatase 5; MTMR5; Myotubularin-related protein 5; Sbf1; SET binding factor 1; SET-binding factor 1
Gene Symbols Sbf1
Host Species Rabbit
Immunogen Recombinant protein (or fragment).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 300147, 6305
Target Species Human, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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