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Description
PA1-739 detects secretory carrier membrane protein 1 (SCAMP 1) from human, mouse and rat samples. PA1-739 has been successfully used in Western blot and immunoprecipitation procedures. By Western blot, this antibody detects an ~31 kDa protein representing SCAMP 1 in rat and mouse brain tissues as well as HeLa cell lysates. PA1-739 immunizing peptide corresponds to amino acid residues 1-17 from human SCAMP 1. This sequence is completely conserved between human, rat, and porcine SCAMP 1. PA1-739 immunizing peptide (Cat. # PEP-105) is available for use in neutralization and control experiments.
Secretory carrier membrane proteins (SCAMPs) are proteins that are components of post-Golgi membranes. These ubiquitously expressed proteins are implicated to function in membrane trafficking. In fibroblasts, SCAMPs are concentrated in compartments that are involved in the recycling of cell surface receptors and endocytosis. In neurons, SCAMPs are associated with synaptic vesicles, secretion granules and transporter vesicles. Of the three known SCAMPs, SCAMP 1 is the most abundant. SCAMP 1 has been shown to be required for the full execution of stable exocytosis in mast cells.
Specifications
| SCAMP1 | |
| Polyclonal | |
| Unconjugated | |
| SCAMP1 | |
| 4930505M11Rik; AI415563; AW122395; SCAMP; SCAMP 37; SCAMP1; SCAMP37; Secretory carrier membrane protein 1; secretory carrier-associated membrane protein 1 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 107767, 29521, 9522 | |
| -20°C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| Immunoprecipitation, Western Blot | |
| 1 mg/mL | |
| PBS with 1mg/mL BSA and 0.05% sodium azide | |
| O15126, P56603, Q8K021 | |
| SCAMP1 | |
| Synthetic Peptide: M(1) S D F D S N P F A D P D L N N P(17) C. | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
Safety and Handling
WARNING: Cancer - www.P65Warnings.ca.gov
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