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Invitrogen™ SCAMP2 Polyclonal Antibody
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Catalog No. PIPA553215
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PIPA553215 100 μL
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Catalog No. PIPA553215 Supplier Invitrogen™ Supplier No. PA553215
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Description

Rabbit Polyclonal Antibody

Immunogen sequence: DPVDVNPFQD PSVTQLTNAP QGGLAEFNPF SETNAATTVP VTQLPGSSQP AVLQPSVEPT QPTPQAVVSA AQAGLLRQQE ELDRKAAELE RKERELQNTV ANLHV Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%.

Secretory carrier membrane proteins (SCAMPs) are proteins that are components of post-Golgi membranes. These proteins are implicated to function in membrane trafficking. In fibroblasts, SCAMPs are concentrated in compartments that are involved in the recycling of cell surface receptors and endocytosis. In neurons, SCAMPs are associated with synaptic vesicles, secretion granules and transporter vesicles. SCAMPs are composed of four central transmembrane regions and a cytoplasmic tail. Of the five known SCAMPs, SCAMPs 1-3 contain cytoplasmic N-terminal regions with NPF repeats. NPF repeats are found to interact with EH domain proteins that function in budding of transport vesicles from the plasma membrane or the Golgi complex. SCAMPs 4 and 5 lack the N-terminal NPF repeats. SCAMPs 1-4 are all ubiquitously coexpressed while SCAMP 5 is only detectable in the brain. Studies show that SCAMP 5 is expressed late in development which is coincident with expansion of mature synapses.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SCAMP2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Scamp2
Gene Accession No. O15127, Q9ERN0
Gene Alias AI875466; I79_023583; Sc2; scamp 2; SCAMP2; Secretory carrier membrane protein 2; secretory carrier-associated membrane protein 2; testis secretory sperm-binding protein Li 219p
Gene Symbols Scamp2
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human SCAMP2. Recombinant protein control fragment (Product #RP-91153).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10066, 24044, 65168
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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