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Invitrogen™ SCD Monoclonal Antibody (CD.E10)
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Catalog No. PIMA527542
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100 μg
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PIMA527542 100 μg
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Catalog No. PIMA527542 Supplier Invitrogen™ Supplier No. MA527542
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Description

Mouse Monoclonal Antibody

SCD Monoclonal Antibody for ELISA, ICC/IF, IP, Western Blot

Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an iron-containing enzyme that catalyzes a rate-limiting step in the synthesis of unsaturated fatty acids. The principal product of SCD is oleic acid, which is formed by desaturation of stearic acid. The ratio of stearic acid to oleic acid has been implicated in the regulation of cell growth and differentiation through effects on cell membrane fluidity and signal transduction. Four SCD isoforms, Scd1 through Scd4, have been identified in mouse. In contrast, only 2 SCD isoforms, SCD1 and SCD5., have been identified in human. SCD1 shares about 85% amino acid identity with all 4 mouse SCD isoforms, as well as with rat Scd1 and Scd2. In contrast, SCD5 shares limited homology with the rodent SCDs and appears to be unique to primates.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SCD
Applications ELISA, Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone CD.E10
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide; pH 7.2
Gene Scd
Gene Accession No. O00767, P07308, P13516
Gene Alias AA589638; ab; acyl-CoA desaturase; Acyl-CoA desaturase 1; acyl-CoA desaturase 2; AI265570; asebia; delta(9)-desaturase; Delta(9)-desaturase 1; delta(9)-desaturase 2; Delta-9 desaturase; delta-9 desaturase 1; Delta-9 desaturase 2; delta-9-desaturase; FADS5; fatty acid desaturase; Fatty acid desaturase 1; fatty acid desaturase 2; HGNC:10571; hSCD1; MSTP008; OTTHUMP00000020280; predicted protein of HQ0998; PRO0998; PRO1933; Scd; Scd1; Scd-1; Scd2; SCDOS; stearoyl-CoA desaturase; stearoyl-CoA desaturase (delta-9-desaturase); stearoyl-CoA desaturase 1; Stearoyl-CoA desaturase 2; stearoyl-CoA desaturase opposite strand; stearoyl-Coenzyme A desaturase 1; stearoyl-Coenzyme A desaturase 2; stearyl-CoA desaturase
Gene Symbols Scd, Scd1
Host Species Mouse
Immunogen Full length human recombinant protein against SCD1.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 20249, 246074, 6319
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG2b
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