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Invitrogen™ SCUBE1 Polyclonal Antibody
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Catalog No. PIPA570696
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PIPA570696 100 μL
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Catalog No. PIPA570696 Supplier Invitrogen™ Supplier No. PA570696
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Description

Rabbit Polyclonal Antibody

This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%.

SCUBE1 is an EGF-related protein with a CUB (C1s-like) domain that is expressed primarily in the developing gonad, nervous system, somites, surface ectoderm and limb buds. The N-terminal EGF-like repeats of SCUBE1 participate in the formation of adhesions in a Ca2+-dependent fashion. In contrast, the C-terminal cysteine-rich motifs and CUB domain can directly bind and antagonize bone morphogenic protein activity; genetic ablation of this region resulted in brain malformation in mice embryos, suggesting SCUBE1 plays a role in brain morphogenesis. SCUBE1 has also been implicated in early craniofacial development in mice.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SCUBE1
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene SCUBE1
Gene Accession No. Q6NZL8
Gene Alias 7330410C13Rik; A630023E24Rik; im:7427863; SCUBE1; signal peptide; Signal peptide, CUB and EGF-like domain-containing protein 1; signal peptide, CUB and EGF-like domain-containing protein 1; LOW QUALITY PROTEIN: signal peptide, CUB and EGF-like domain-containing protein 1; signal peptide, CUB domain and EGF like domain containing 1; signal peptide, CUB domain, EGF-like 1; signal peptide-CUB domain-EGF-related 1
Gene Symbols SCUBE1
Host Species Rabbit
Immunogen synthetic peptide directed towards the C-terminal region of mouse SCUBE1.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 64706
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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