Invitrogen™ SCUBE1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA570696

Catalog No. PIPA570696

Description

This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%.

SCUBE1 is an EGF-related protein with a CUB (C1s-like) domain that is expressed primarily in the developing gonad, nervous system, somites, surface ectoderm and limb buds. The N-terminal EGF-like repeats of SCUBE1 participate in the formation of adhesions in a Ca2+-dependent fashion. In contrast, the C-terminal cysteine-rich motifs and CUB domain can directly bind and antagonize bone morphogenic protein activity; genetic ablation of this region resulted in brain malformation in mice embryos, suggesting SCUBE1 plays a role in brain morphogenesis. SCUBE1 has also been implicated in early craniofacial development in mice.

Specifications

• Antigen: SCUBE1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SCUBE1
• Gene Alias: 7330410C13Rik; A630023E24Rik; im:7427863; SCUBE1; signal peptide; Signal peptide, CUB and EGF-like domain-containing protein 1; signal peptide, CUB and EGF-like domain-containing protein 1; LOW QUALITY PROTEIN: signal peptide, CUB and EGF-like domain-containing protein 1; signal peptide, CUB domain and EGF like domain containing 1; signal peptide, CUB domain, EGF-like 1; signal peptide-CUB domain-EGF-related 1
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 64706
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q6NZL8
• Gene Symbols: SCUBE1
• Immunogen: synthetic peptide directed towards the C-terminal region of mouse SCUBE1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov