Invitrogen™ SCUBE2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA520991

Catalog No. PIPA520991

Description

A suggested positive control is Daudi cell lysate. PA5-20991 can be used with blocking peptide PEP-1105.

SCUBE2 is a member of a family of secreted glycoproteins that contain N-terminal EGF-like repeats and C-terminal cysteine-rich motifs and CUB domain and are expressed in embryonic neuroectoderm and vascular epithelium. SCUBE2 is a close homolog to SCUBE1 and can form a heterodimeric complex with SCUBE1. SCUBE2 is thought to participate in the Hedgehog signaling pathway by specifically interacting with Sonic Hedgehog (SHH) and the receptor PTCH1, enhancing the SHH signaling activity in the raft microdomains of the plasma membrane, and may thus play important roles in organ development and tumor progression.

Specifications

• Antigen: SCUBE2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SCUBE2
• Gene Alias: CEGB1; CEGF1; CEGP1; Protein CEGP1; RGD1563998; Scube/You; SCUBE2; Scube2-ps1; signal peptide; Signal peptide, CUB and EGF-like domain-containing protein 2; signal peptide, CUB domain and EGF like domain containing 2; signal peptide, CUB domain, EGF-like 2; signal peptide, CUB domain, EGF-like 2, pseudogene 1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 499241, 57758
• Content And Storage: Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q9NQ36
• Gene Symbols: SCUBE2
• Immunogen: A 17 amino acid peptide near the center of human SCUBE2.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG