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Invitrogen™ SDHB Monoclonal Antibody (21A11AE7)
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Catalog No. 459230
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Catalog No. Quantity
45-923-0 100 μL
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Catalog No. 45-923-0 Supplier Invitrogen™ Supplier No. 459230
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Description

Mouse Monoclonal Antibody

Positive control: Human heart mitochondria.

Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SDHB
Applications Flow Cytometry, Immunohistochemistry, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 21A11AE7
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation HEPES buffered saline with 0.02% sodium azide
Gene Sdhb
Gene Accession No. P21912, P21913, Q3T189, Q9CQA3
Gene Alias 0710008N11Rik; CWS2; fj46d06; FLJ92337; I79_022285; Ip; iron-sulfur subunit; iron-sulfur subunit of complex II; OTTHUMP00000044624; PGL4; SDH; SDH1; SDH2; Sdhb; SDHB protein; SDHB; sdhB; SDHIP; succinate dehydrogenase [ubiquinone] iron-sulfur subunit; Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; succinate dehydrogenase complex iron sulfur subunit B; succinate dehydrogenase complex subunit B; succinate dehydrogenase complex subunit B, iron sulfur (Ip); succinate dehydrogenase complex, subunit B, iron sulfur (Ip); succinate dehydrogenase Ip subunit; succinate dehydrogenase iron-protein subunit; wu:fj46d06
Gene Symbols Sdhb
Host Species Mouse
Immunogen Bovine Heart Complex II, with traces of Complex III.
Purification Method IgG fraction
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 286840, 298596, 6390, 67680
Target Species Human, Mouse, Rat, Bovine
Content And Storage 4°C
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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