SDHB Monoclonal Antibody (OTI1E4), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA808115

Catalog No. 50-168-1915

Description

Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.

Specifications

• Antigen: SDHB
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: P21912
• Gene Symbols: SDHB
• Immunogen: Full length human recombit protein of human SDHB produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Western Blot
• Clone: OTI1E4
• Conjugate: Unconjugated
• Gene: SDHB
• Gene Alias: CWS2, IP, PGL4, SDH, SDH1, SDH2, SDHIP
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6390
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid