SDHB Monoclonal Antibody (OTI1E4), TrueMAB™, OriGene

Catalog No.	Quantity
50-168-1915	100 μL

Catalog No. 50-168-1915 Supplier OriGene Supplier No. TA808115

Description

Mouse Monoclonal Antibody

Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.

Specifications

• Antigen: SDHB
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI1E4
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: SDHB
• Gene Accession No.: P21912
• Gene Alias: CWS2, IP, PGL4, SDH, SDH1, SDH2, SDHIP
• Gene Symbols: SDHB
• Host Species: Mouse
• Immunogen: Full length human recombit protein of human SDHB produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 6390
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1