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Invitrogen™ SEC61B Polyclonal Antibody
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Catalog No. PA3015
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100 μL
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Catalog No. Quantity
PA3-015 100 μL
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Catalog No. PA3-015 Supplier Invitrogen™ Supplier No. PA3015
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Description

Rabbit Polyclonal Antibody

PA3-015 detects human, canine and porcine, and rat sec61 beta from microsomes and shows no cross-reactivity with other sec61 isoforms. PA3-015 has been successfully used in Western blot procedures. By Western blot, this antibody detects an ~14 kDa protein representing sec61 beta from pig microsomes. The PA3-015 immunogen is a synthetic peptide corresponding to residues M(1) P G P T P S G T N V G S S G R S P S K(20) of canine sec61 beta. This sequence is completely conserved between human, mouse, and canine.

The Sec61 complex is responsible for translocation of proteins across the rough endoplasmic reticulum membrane. Sec61 is composed of three subunits: alpha, beta, and gamma; that associate to form a heterotrimer. Multiple heterotrimers associate forming the ER translocon. Sec61 alpha is a polytopic protein that has ten membrane-spanning loops. Sec61 has been found to be tightly associated with membrane bound ribosomes, either directly or through adaptor proteins, and is required for assembly of membrane and secretory proteins.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SEC61B
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation Whole serum with 0.05% sodium azide
Gene SEC61B
Gene Accession No. P60467, P60468, Q9CQS8
Gene Alias 1190006C12Rik; AI326121; AW122942; protein translocation complex beta; protein translocation complex beta subunit; protein transport protein SEC61 beta subunit; protein transport protein Sec61 subunit beta; sec61 beta; Sec61 beta subunit; Sec61 complex, beta subunit; SEC61 translocon beta subunit; SEC61 translocon subunit beta; Sec61b
Gene Symbols SEC61B
Host Species Rabbit
Immunogen Synthetic peptide corresponding to residues M(1) P G P T P S G T N V G S S G R S P S K(20) of canine sec61 beta.
Purification Method NA
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 100511362, 10952, 298068, 404018, 66212
Target Species Human, Mouse, Rat, Canine, Pig
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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