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Invitrogen™ SEMA3C Polyclonal Antibody
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Catalog No. PIPA575455
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100 μL
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PIPA575455 100 μL
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Catalog No. PIPA575455 Supplier Invitrogen™ Supplier No. PA575455
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Description

Rabbit Polyclonal Antibody

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

The SEMA3C gene encodes the protein semaphorin 3C, a member of the semaphorin family known for its roles in axonal guidance, cellular signaling, and vascular development. Semaphorin 3C is involved in guiding neurons during development by serving as a repulsive cue, helping establish proper neural network formation through interaction with neuropilin and plexin receptors. It also plays crucial roles in angiogenesis and cardiac development by influencing endothelial cell behavior and migration. In the context of cancer, SEMA3C is implicated in tumor progression, where its dysregulation can promote tumor cell invasion and metastasis by modifying the extracellular matrix and affecting cellular adhesion. Research has demonstrated that SEMA3C can alter the tumor microenvironment, making it a potential target for cancer therapies aimed at inhibiting metastasis and controlling tumor growth. Understanding SEMA3C's function in various biological processes continues, highlighting its significance in developmental biology and disease modulation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SEMA3C
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene SEMA3C
Gene Accession No. Q62181, Q99985
Gene Alias 1110036B02Rik; sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C; sema E; Sema3c; Semae; semaphorin 3C; semaphorin E; semaphorin-3C; Semaphorin-E; SemE
Gene Symbols SEMA3C
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids 713-751 of Human SEMA3C.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10512, 20348, 296787
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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