Invitrogen™ SENP3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA531055

Catalog No. PIPA531055

Description

Recommended positive controls: Raji, K562, THP-1. Predicted reactivity: Mouse (100%), Rat (99%), Xenopus laevis (87%), Chimpanzee (100%), Bovine (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins is required for numerous biologic processes. SUMO-specific proteases, such as SENP3, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates.

Specifications

• Antigen: SENP3
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Senp3
• Gene Alias: AA408656; DKFZP586K0919; DKFZp762A152; SENP3; sentrin/SUMO-specific protease 3; sentrin/SUMO-specific protease SENP3; Sentrin-specific protease 3; Smt3ip; Smt3ip1; Smt3-specific isopeptidase 1; SSP3; SUMO specific peptidase 3; SUMO/sentrin specific peptidase 3; SUMO/sentrin specific protease 3; SUMO1/sentrin/SMT3 specific peptidase 3; SUMO1/sentrin/SMT3 specific protease 3; SUMO-1-specific protease 3; SUSP3; Ulp1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 26168
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q9H4L4
• Gene Symbols: Senp3
• Immunogen: Recombinant fragment corresponding to a region within amino acids 382 and 574 of Human SENP3.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG