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Invitrogen™ SERCA1 ATPase Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA578834
Description
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: Rat Skeletal Muscle Tissue, PANC Cell, U87 Cell. IHC: Human Placenta Tissue, Rat Skeletal Muscle Tissue.
ATP dependent calcium pumps are responsible, in part, for the maintenance of low cytoplasmic free calcium concentrations. The ATP pumps that reside in intracellular organelles are encoded by a family of structurally related enzymes, termed the sarcoplasmic or endoplasmic reticulum calcium (SERCA) ATPases. The SERCA1 gene is exclusively expressed in type II (fast) skeletal muscle. The SERCA2 gene is subject to tissue dependent processing which is responsible for the generation of SERCA2a muscle-specific form expressed in type I (slow) skeletal, cardiac and smooth muscle and the SERCA2b isoform expressed in all cell types. The SERCA3 gene is not as well characterized and is found in non-muscle cells.
Specifications
SERCA1 ATPase | |
Polyclonal | |
Unconjugated | |
ATP2A1 | |
adult Ca2+ ATPase; ATP2A; ATP2A1; ATP2A3; ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1; ATPase, Ca++ transporting, cardiac muscle, fast twitch 1; ATPase, Ca++ transporting, ubiquitous; Ca2+ ATPase; calcium pump 1; Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform; endoplasmic reticulum class 1/2 Ca(2+) ATPase; neonatal Ca2+ ATPase; sarcoplasmic/endoplasmic reticulum calcium ATPase 1; SERCA; SERCA ATPase; Serca1; SERCA1a; SR Ca(2+)-ATPase 1 | |
Rabbit | |
Antigen affinity chromatography | |
RUO | |
116601, 11937, 487 | |
-20°C | |
Lyophilized |
Immunohistochemistry (Paraffin), Western Blot | |
500 μg/mL | |
PBS with 5 mg BSA and 0.05 mg sodium azide, 0.05 mg thimerosal | |
O14983, Q64578, Q8R429 | |
ATP2A1 | |
A synthetic peptide corresponding to a sequence in the middle region of human SERCA1 ATPase (665-680aa EQREACRRACCFARVE). | |
100 μg | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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