Invitrogen™ SERPINH1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA595231

Catalog No. PIPA595231

Description

Human Hsp47 shares 97% amino acid (aa) sequence identity with both mouse and rat Hsp47. Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: human A431 whole cell, human SK-N-SH whole cell, human Hela whole cell, rat lung tissue, rat kidney tissue, rat L6 whole cell, mouse lung tissue, mouse NIH/3T3 whole cell. IHC: human breast cancer tissue, human endometrial adenocarcinoma tissue, human esophageal squamous carcinoma tissue, human liver cancer tissue, human spleen tissue, human lung adenocarcinoma tissue. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

SERPINH1 is a member of the serpin superfamily of serine proteinase inhibitors, and its expression is induced by heat shock. The SERPINH1 protein localizes to the endoplasmic reticulum lumen and binds collagen; thus it is thought to be a molecular chaperone involved in the maturation of collagen molecules. Autoantibodies to SERPINH1 have been found in patients with rheumatoid arthritis.

Specifications

• Antigen: SERPINH1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SERPINH1
• Gene Alias: 47 kDa heat shock protein; arsenic-transactivated protein 3; AsTP 3; AsTP3; BERF-1; beta enolase repressor factor 1; CBP 1; CBP 2; CBP1; CBP2; Cell proliferation-inducing gene 14 protein; collagen binding protein 1; collagen binding protein 2; collagen-binding protein; Colligen; Colligin; Colligin 1; Colligin 2; colligin-1; colligin-2; GP46; heat shock protein 47; HGNC 1547; Hsp 47; HSP47; J6; OI10; PIG 14; PIG14; PPROM; RA A47; RA-A47; rheumatoid arthritis antigen A-47; rheumatoid arthritis-related antigen RA-A47; serine (or cysteine) peptidase inhibitor, clade H, member 1; serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 1; serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1); serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 2; serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 2, (collagen-binding protein 2); serine (or cysteine) proteinase inhibitor, clade H, member 1; serine protease inhibitor J6; serine proteinase inhibitor, clade H (heat shock protein 47), member 1; serpin family H member 1; serpin H1; serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1); serpin peptidase inhibitor, clade H, member 1; SERPINH1; SERPINH2
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 12406, 29345, 871
• Content And Storage: -20°C
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 500 μg/mL
• Formulation: PBS with 5mg BSA and 0.05mg sodium azide
• Gene Accession No.: P19324, P29457, P50454
• Gene Symbols: SERPINH1
• Immunogen: E.coli-derived human Hsp47 recombinant protein (Position: D247-L418).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov