SERPINI1 Monoclonal Antibody (OTI1A5), TrueMAB™, OriGene

Catalog No.	Quantity
50-168-4434	100 μL

Catalog No. 50-168-4434 Supplier OriGene Supplier No. TA812171

Description

Mouse Monoclonal Antibody

This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a domitly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Specifications

• Antigen: SERPINI1
• Applications: Western Blot
• Classification: Monoclonal
• Clone: OTI1A5
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene: SERPINI1
• Gene Accession No.: Q99574
• Gene Alias: PI12, neuroserpin
• Gene Symbols: SERPINI1
• Host Species: Mouse
• Immunogen: Human recombit protein fragment corresponding to amino acids 17-410 of human SERPINI1 produced in E.coli.
• Purification Method: Affinity Chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 5274
• Target Species: Human
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1