SESN1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group Inc 216681AP150UL

Catalog No. 50-173-3545

Description

This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Specifications

• Antigen: SESN1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SESN1
• Gene Alias: p53 regulated protein PA26, PA26, RP11 787I22.1, SESN1, SEST1, sestrin 1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 140742, 27244, 294518
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.33 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: P58006, Q9Y6P5
• Gene Symbols: SESN1
• Immunogen: SESN1 Fusion Protein Ag16462
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG