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SESN1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group Inc 216681AP150UL

Encompass_Preferred

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Catalog No. 50-173-3545


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Description

Description

This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Specifications

Specifications

SESN1
Polyclonal
Unconjugated
SESN1
p53 regulated protein PA26, PA26, RP11 787I22.1, SESN1, SEST1, sestrin 1
Rabbit
Antigen Affinity Chromatography
RUO
140742, 27244, 294518
-20°C
Liquid
Western Blot
0.33 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P58006, Q9Y6P5
SESN1
SESN1 Fusion Protein Ag16462
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG
SDS
Documents
Product Certifications
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