SESN1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 216681AP150UL
DescriptionThis gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
|p53 regulated protein PA26, PA26, RP11 787I22.1, SESN1, SEST1, sestrin 1|
|Antigen Affinity Chromatography|
|140742, 27244, 294518|
|PBS with 50% glycerol and 0.1% sodium azide; pH 7.3|
|SESN1 Fusion Protein Ag16462|
|Human, Mouse, Rat|
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