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SESN1 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody
Supplier: Proteintech Group Inc 216681AP150UL

Description
This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.Specifications
SESN1 | |
Polyclonal | |
Unconjugated | |
SESN1 | |
p53 regulated protein PA26, PA26, RP11 787I22.1, SESN1, SEST1, sestrin 1 | |
Rabbit | |
Antigen Affinity Chromatography | |
RUO | |
140742, 27244, 294518 | |
-20°C | |
Liquid |
Western Blot | |
0.33 mg/mL | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
P58006, Q9Y6P5 | |
SESN1 | |
SESN1 Fusion Protein Ag16462 | |
150 μL | |
Primary | |
Human, Mouse, Rat | |
Antibody | |
IgG |
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