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SF3b145/SAP145 Rabbit anti-Human, Polyclonal, Bethyl Laboratories

Catalog No. 501560811
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50-156-0811 100 μL
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Catalog No. 50-156-0811 Supplier Bethyl Laboratories, Inc Supplier No. A301605A
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Description

Rabbit Polyclonal Antibody

The recommended shelf life for this product is 1 year from date of receipt. Application Note: For IHC, epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

Subunit of the splicing factor SF3B required for ′A′ complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the ′E′ complex. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron.

Specifications

Antigen SF3b145/SAP145
Applications Immunohistochemistry, Immunoprecipitation, Western Blot
Classification Polyclonal
Concentration 0.2 mg/ml
Conjugate Unconjugated
Formulation TBS with 0.1% BSA and 0.09% sodium azide
Gene SF3B2
Gene Accession No. Q13435
Gene Alias Splicing factor 3B subunit 2, Pre-mRNA-splicing factor SF3b 145 kDa subunit, SF3b145, SF3b150, Spliceosome-associated protein 145, SAP 145, SF3B2, SAP145
Gene Symbols SF3B2
Host Species Rabbit
Immunogen Between 775 and 825
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10992
Target Species Human
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG
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