Invitrogen™ SGPL1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA112722

Catalog No. 01-674-851

Description

By Western blot, PA1-12722 detects a ~64 kDa protein representing S1P lyase 1 from MDBK cell lysate.

Sphingosine-1-phosphate lyase cleaves phosphorylated sphingoid bases, such as sphingosine-1 phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis. The catalytic activity of sphingosine 1- phosphate lyase converts sphingosine 1-phosphate to phosphoethanolamine and palmitaldehyde using Pyridoxal phosphate as a co-factor. Sphingosine 1-phosphate lyase is a type III membrane protein found in the endoplasmic reticulum. Sphingosine 1-phosphate lyase is found primarily in the liver and kidney. Sphingosine 1-phosphate lyase belongs to the group II decarboxylase family.

Specifications

• Antigen: SGPL1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SGPL1
• Gene Alias: AI428538; D10Xrf456; FLJ13811; hSPL; KIAA1252; mSPL; S1PL; Sgpl1; Spgl1; sphingosine phosphate lyase 1; sphingosine-1-phosphate aldolase; Sphingosine-1-phosphate lyase 1; sphingosine-1-phosphate lyase 1-like protein; spl; SPL 1; SP-lyase 1; zgc:162153
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 20397, 286896, 522515, 8879
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 1.0 mg/mL
• Formulation: PBS with 0.08% sodium azide
• Gene Accession No.: O95470, Q8CHN6, Q8R0X7
• Gene Symbols: SGPL1
• Immunogen: Synthetic peptide corresponding to sphingosine 1-phosphate lyase 1.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Bovine
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov