SH3BP4 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Catalog No.	Quantity
50-173-1723	150 μL

Catalog No. 50-173-1723 Supplier Proteintech Group Inc Supplier No. 176911AP150UL

Description

Rabbit Polyclonal Antibody

SH3BP4 was initially isolated as a novel cDNA using differential display analysis using cultured human corneal fibroblasts. The protein contains three Asn-Pro-Phe (NPF) motifs, an SH3 domain, a PXXP motif, a bipartite nuclear targeting signal, and a tyrosine phosphorylation site. SH3BP4 has been shown to interact with specific endocytic proteins such as clathrin, dynamin, and the transferrin receptor (TfR) and localizes to TfR-containing coated pits and vesicles. It is thought to be involved in cargo-specific control of clathrin-mediated endocytosis, specifically controlling the internalization of TfR. At least two isoforms of SH3BP4 are known to exist.

Specifications

• Antigen: SH3BP4
• Applications: Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
• Classification: Polyclonal
• Concentration: 0.18 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: SH3BP4
• Gene Accession No.: Q921I6, Q9JJS5, Q9P0V3
• Gene Alias: BOG25, EH binding protein 10, EHB10, SH3 domain binding protein 4, SH3BP4, TTP
• Gene Symbols: Sh3bp4
• Host Species: Rabbit
• Immunogen: SH3BP4 Fusion Protein Ag11847
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 23677, 64634, 98402
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG