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Invitrogen™ SH3PXD2A Polyclonal Antibody
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Catalog No. PIPA5117156
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100 μL
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PIPA5117156 100 μL
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Catalog No. PIPA5117156 Supplier Invitrogen™ Supplier No. PA5117156
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Description

Rabbit Polyclonal Antibody

Positive Samples: HeLa Immunogen sequence: TKKEWEGPAT SYMTCSAYQK VQDSEISFPA GVEVQVLEKQ ESGWWYVRFG ELEGWAPSHY LVLDENEQPD PSGKELDTVP AKGRQNEGKS DSLEKIERRV QALNTVNQSK KATPPIPSKP PGGFGKTSGT PAVKMRNGVR QVAVRPQSVF VSPPPKDNNL SCALRRNESL TATDGLRGVR RNSSFSTARS AAAEAKGRLA ERAASQGSDS PLLPAQRNSI PVSPVRPKPI EKSQFIHNNL KDVYVSIADY EGDEETAGFQ EGVSMEVLER NPNGWWYCQI LDGVKPFKGW VPSNYLEKKN.

Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases (ADAMs), NADPH oxidases (NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1- or NOX3-dependent reactive oxygen species (ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of amyloid-beta peptide.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SH3PXD2A
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 5.14 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Sh3pxd2a
Gene Accession No. O89032, Q5TCZ1
Gene Alias 2310014D11Rik; AA589508; Adapter protein TKS5; adaptor protein TKS5; AI256723; AI413738; C230050L11; EG329070; FISH; Five SH3 domain-containing protein; five SH3 domains; Gm5098; KIAA0418; SH3 and PX domain-containing protein 2A; SH3 and PX domains 2A; SH3 multiple domains 1; SH3 multiple domains protein 1; Sh3md1; SH3PXD2A; Tks5; TSK5; Tyrosine kinase substrate with five SH3 domains
Gene Symbols Sh3pxd2a
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 806-1105 of human SH3PXD2A (NP_0554462).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14218, 9644
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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