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  5. Tocris Bioscience™ Silodosin

Tocris Bioscience™ Silodosin
GREENER_CHOICE

Catalog No. 666350
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Selective α1A adrenoceptor antagonist (Ki = 0.036 nM)

Silodosin is a selective α1A adrenoceptor antagonist (Ki = 0.036 nM). Displays >55 fold selectivity for α1A over α1B and α1D. Inhibits norepinephrine-induced [Ca2+]I increase in α1A expressing CHO cells (IC50 = 0.32 nM). Inhibits norepinephrine-induced contraction of isolated human prostate tissue.

Specifications

Chemical Name or Material 2,3-Dihydro-1-(3-hydroxypropyl)-5-[(2R)-2-[[2-[2-(2,2,2-trifluoroethoxy)phenoxy]ethyl]amino]propyl]-1H-indole-7-carboxamide
CAS 160970-54-7
Quantity 50 mg
Molecular Formula C25H32F3N3O4
Formula Weight 495.53
Purity 98%
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