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MilliporeSigma™ Simplicon™ Reprogramming RNA (OKSG)

Catalog No. SCR549 Shop All MilliporeSigma Products
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Description

For use as transfection reagent.

  • Safe, efficient
  • Stem cell type: Induced pluripotent stem cells
  • Generates integration free, virus-free human iPS cell
  • Single transfection step of self-replicating synthetic RNA for Oct4, Klf4, Sox2, Glis1
  • Integration free, footprint free iPS cells
  • No risk of genomic integration
  • Safe, virus free, synthetic polycistronic RNA replicon (all four reprogramming factors in 1 RNA str)
  • Only 1 day transfection required
  • RNA replicon is able to self-replicate, elliminating need for laborious daily transfection of multiple individual mRNAs over 14 day period
  • Efficient rapid reprogramming
  • No screening required to ensure viral remnants are not present
  • Controlled elimination of synthetic RNA replicon by removal of B18R protein
  • Validated for reprogramming in feeder-based feeder-free culture conditions
TRUSTED_SUSTAINABILITY

Specifications

Quantity 1 Kit
Content And Storage >-70°C
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