Invitrogen™ SIRP gamma Monoclonal Antibody (OX-119)

Catalog No.	Quantity
PIMA528217	200 μg

Catalog No. PIMA528217

Supplier: Invitrogen™ MA528217

Description

Mouse Monoclonal Antibody

Mouse anti Human CD172g antibody, clone OX119 recognizes human SIRP gamma, a 55 kDa signal regulatory protein which is a member of the immunoglobulin gene superfamily.

SIRP gamma (CD172g) recognizes a 55 kDa signal regulatory protein which is a member of the immunoglobulin gene superfamily. SIRP gamma is expressed on most T lymphocytes and a subset of B-cells but is absent on myeloid cells. CD172g has a truncated cytoplasmic tail, which is similar to SIRP beta, but unlike SIRP beta CD172g does not require DAP12 for expression at the cell surface. CD172g, like SIRP alpha, binds to CD47 inducing apoptosis. SIRP gamma is also involved in the negative regulation of receptor tyrosine kinase-coupled signalling.

Specifications

• Antigen: SIRP gamma
• Applications: Flow Cytometry, Immunoprecipitation
• Classification: Monoclonal
• Clone: OX-119
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 0.09% sodium azide
• Gene: SIRPG
• Gene Accession No.: Q9P1W8
• Gene Alias: bA77C3.1; CD172 antigen-like family member B; CD172 gamma; CD172g; CD172g antigen; RP11-77C3.2; signal regulatory protein gamma; signal-regulatory protein beta 2; signal-regulatory protein beta-2; Signal-regulatory protein gamma; SIRP beta 2; SIRPB2; SIRP-B2; SIRP-beta-2; SIRPG; SIRPgamma; SIRP-gamma
• Gene Symbols: SIRPG
• Host Species: Mouse
• Immunogen: Purified recombinant SIRP gamma CD4.
• Purification Method: Protein A
• Quantity: 200 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 55423
• Target Species: Human
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG1