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SIRT2 Polyclonal Antibody, Active Motif™
SDP

Rabbit Polyclonal Antibody

Supplier:  Active Motif 61046

Encompass

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Catalog No. 50-199-4140


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Description

Description

SIRT2 Polyclonal Antibody for Western Blot, ICC/IF

The SIRT2 protein (also known as Sirtuin for Silent Mating Type Information 2-Homolog) is a NAD-dependent deacytylase (NDAC) that has been shown to control gene silencing, cell cycle, and DNA damage repair. It is believed that SIRT2 may act as a tumor suppressor in human gliomas and may also serve as a novel molecular marker for these cells. SIRT2 has also been shown to act as a redox sensor to help regulate muscle gene expression in response to food intake and exercise. SIRT2 acts in the phosphorylation cascade involving mitosis where SIRT2 is phosphorylated in late G2 phase, during M phase, and into cytokinesis.
Specifications

Specifications

SIRT2
Polyclonal
Unconjugated
SIRT2
5730427M03Rik; 5E5 antigen; mSIR2L2; NAD-dependent deacetylase sirtuin-2; NAD-dependent protein deacetylase sirtuin-2; Regulatory protein SIR2 homolog 2; silent information regulator 2; silent mating type information regulation 2, (S.cerevisiae, homolog)-like; sirtuin 2; SIR2; SIR2L; SIR2L2; SIR2-like protein 2; sir2-related protein type 2; SIRT2; sirtuin 2; sirtuin type 2; sirtuin-2
Rabbit
10 μL
Primary
Mouse
Antibody
IgG
Immunocytochemistry, Immunofluorescence, Western Blot
Conc. Not Determined
whole serum with 30% glycerol and 0.035% sodium azide; pH
Q8VDQ8
SIRT2
This SIRT2 antibody was raised against a peptide within the C-terminal region of mouse SIRT2 protein.
RUO
64383
-20°C, Avoid Freeze/Thaw Cycles
Liquid
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