SIRT2 Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-199-4140	Active Motif 61046	10 μL
50-199-4139	Active Motif 61045	100 μL

Description

SIRT2 Polyclonal Antibody for Western Blot, ICC/IF

The SIRT2 protein (also known as Sirtuin for Silent Mating Type Information 2-Homolog) is a NAD-dependent deacytylase (NDAC) that has been shown to control gene silencing, cell cycle, and DNA damage repair. It is believed that SIRT2 may act as a tumor suppressor in human gliomas and may also serve as a novel molecular marker for these cells. SIRT2 has also been shown to act as a redox sensor to help regulate muscle gene expression in response to food intake and exercise. SIRT2 acts in the phosphorylation cascade involving mitosis where SIRT2 is phosphorylated in late G2 phase, during M phase, and into cytokinesis.

Specifications

• Antigen: SIRT2
• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Mouse
• Gene Accession No.: Q8VDQ8
• Gene ID (Entrez): 64383
• Immunogen: This SIRT2 antibody was raised against a peptide within the C-terminal region of mouse SIRT2 protein.
• Primary or Secondary: Primary
• Product Type: Antibody

• Concentration: Conc. Not Determined
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: whole serum with 30% glycerol and 0.035% sodium azide; pH
• Gene Alias: 5730427M03Rik; 5E5 antigen; mSIR2L2; NAD-dependent deacetylase sirtuin-2; NAD-dependent protein deacetylase sirtuin-2; Regulatory protein SIR2 homolog 2; silent information regulator 2; silent mating type information regulation 2, (S.cerevisiae, homolog)-like; sirtuin 2; SIR2; SIR2L; SIR2L2; SIR2-like protein 2; sir2-related protein type 2; SIRT2; sirtuin 2; sirtuin type 2; sirtuin-2
• Gene Symbols: SIRT2
• Isotype: IgG
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Gene: SIRT2