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SIRT2 Rabbit anti-Mouse, Unconjugated, Polyclonal, Active Motif™ 
Rabbit Polyclonal Antibody
$116.85 - $356.95
Specifications
| Monoclonal or Polyclonal | Polyclonal |
|---|---|
| Primary or Secondary | Primary |
| Antigen | SIRT2 |
| Conjugate | Unconjugated |
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Catalog Number | Mfr. No. | Quantity | Price | Quantity & Availability | |||||
|
50-199-4140
|
Active Motif
61046 |
10 μL |
Each for $116.85
|
|
50-199-4139
|
Active Motif
61045 |
100 μL |
Each for $356.95
|
|
Description
The SIRT2 protein (also known as Sirtuin for Silent Mating Type Information 2-Homolog) is a NAD-dependent deacytylase (NDAC) that has been shown to control gene silencing, cell cycle, and DNA damage repair. It is believed that SIRT2 may act as a tumor suppressor in human gliomas and may also serve as a novel molecular marker for these cells. SIRT2 has also been shown to act as a redox sensor to help regulate muscle gene expression in response to food intake and exercise. SIRT2 acts in the phosphorylation cascade involving mitosis where SIRT2 is phosphorylated in late G2 phase, during M phase, and into cytokinesis.Specifications
| Polyclonal | |
| Primary | |
| SIRT2 | |
| Unconjugated |
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