Invitrogen™ SIRT6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA116957

Catalog No. 01-950-186

Description

PA1-16957 is specific for the ~39 kDa SIRT6 protein. A higher molecular weight band at ~59 kDa may be seen with lower dilutions such as 2 μg/mL. Suggested positive control: antigen standard for SIRT6 (transient overexpression lysate), Hela whole cell extract.

Sirtuins regulate epigenetic gene silencing. SIRT6 (Mono-ADP-ribosyltransferase sirtuin-6), a mouse Sir2 homolog, is a chromatin-associated nuclear ADP-ribosyltransferase protein. It appears to be involved in DNA repair and may also play a role in human aging.

Specifications

• Antigen: SIRT6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SIRT6
• Gene Alias: 2810449N18Rik; AI043036; NAD-dependent deacetylase sirtuin-6; NAD-dependent protein deacetylase sirtuin-6; Regulatory protein SIR2 homolog 6; SIR2; SIR2 like 6; Sir2l6; SIR2-like protein 6; sir2-related protein type 6; Sirt6; sirtuin 6; sirtuin type 6
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51548
• Content And Storage: 4°C, do not freeze
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1.05 mg/mL
• Formulation: Phosphate, tris citrate with 0.1% sodium azide; pH 7-8
• Gene Accession No.: Q8N6T7
• Gene Symbols: SIRT6
• Immunogen: Synthetic peptide between amino acids 300-355 of the human SIRT6 protein.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG