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Tocris Bioscience™ SIS17
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Catalog No. 796950
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Catalog No. Quantity
79-695-0 50 mg
79-691-0 10 mg
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Catalog No. 79-695-0 Supplier Tocris Bioscience™ Supplier No. 7969/50
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Description

Selective HDAC11 inhibitor

SIS17 is a selective HDAC11 inhibitor (IC50 = 0.83 μM). Inhibits demyristoylation of serine hydroxymethyl transferase 2 with no detectable activity at other HDAC subtypes. Combination with Oxaliplatin (Cat. No. 2623) increases cytotoxicity to K562 cells; improves survival of Oxaliplatin-treated 769P cells. Cell permeable.

Specifications

Chemical Name or Material N'-Hexadecylthiophene-2-carbohydrazide
CAS 2374313-54-7
Quantity 50 mg
Target HDAC11
Molecular Formula C21H38N2OS
Purity 0.95
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