SLAM/CD150 Rabbit anti-Human, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Supplier:  Proteintech Group Inc 109492AP150UL

Catalog No. 50-172-6736

Description

CD150, designated SLAM (Signaling Lymphocyte Activation Molecule) or CDw150, belongs to the immunoglobulin gene superfamily and is involved in T cell stimulation. SLAM is constitutively expressed on peripheral blood memory T cells, T cell clones, immature thymocytes, and a proportion of B cells, and is rapidly induced on naive T cells after activation. Activated B cells express the membrane bound form, the soluble form and the cytoplasmic isoforms of SLAM. It is suggested that signalling through homophilic SLAM-SLAM binding during B to B and B to T cell interactions enhances the expansion and differentiation of activated B cells. Reports suggest that the extracellular domain of CD150 is the receptor for the measles virus and acts as a co-activator on T cells and B cells.

Specifications

• Antigen: SLAM/CD150
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLAMF1
• Gene Alias: CD150, CDw150, IPO 3, SLAM, SLAMF1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 6504
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.31 mg/mL
• Formulation: PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
• Gene Accession No.: Q13291
• Gene Symbols: SLAMF1
• Immunogen: SLAM/CD150 Fusion Protein Ag1386
• Quantity: 150 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG