Invitrogen™ SLC16A13 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA536464

Catalog No. PIPA536464

Description

This antibody detects endogenous protein at a molecular weight of 40 kDa. Purity is >95% by SDS-PAGE.

Monocarboxylates, such as lactate and pyruvate, play an integral role in cellular metabolism. Lactic acid is produced in large quantities as a result of glycolysis, which provides the majority of ATP to cells under normal physiological conditions. However, accumulation of lactic acid leads to a decrease in intracellular pH and, thus, to a cessation of glycolysis. In order for glycolysis to continue at a high rate, lactic acid must be transported out of the cell. This transport process is carried out by a family of monocarboxylate transporters (MCTs), which function as proton symports and are stereoselective for L-lactate. MCT13 (Monocarboxylate transporter 13), also known as SLC16A13 (Solute carrier family 16 member 13), is a 426 amino acid multi-pass membrane protein that belongs to the MCT transport family. Functioning as a proton-linked monocarboxylate transporter, MCT13 catalyzes the rapid transports of molecules, such as lactate, across the plasma membrane.

Specifications

• Antigen: SLC16A13
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLC16A13
• Gene Alias: 1700007D07Rik; MCT 13; MCT13; monocarboxylate transporter; Monocarboxylate transporter 13; monocarboxylic acid transporter 13; MOT13; Slc16a13; solute carrier family 16 (monocarboxylic acid transporters), member 13; solute carrier family 16 member 13; solute carrier family 16, member 13; solute carrier family 16, member 13 (monocarboxylic acid transporter 13)
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 201232, 287451, 69309
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q66HE2, Q7RTY0, Q8CE94
• Gene Symbols: SLC16A13
• Immunogen: Synthetic peptide corresponding to amino acids 381-426 of Human SLC16A13.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov