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Invitrogen™ SLC16A13 Polyclonal Antibody
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Catalog No. PIPA536464
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PIPA536464 100 μL
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Catalog No. PIPA536464 Supplier Invitrogen™ Supplier No. PA536464
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Description

Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 40 kDa. Purity is >95% by SDS-PAGE.

Monocarboxylates, such as lactate and pyruvate, play an integral role in cellular metabolism. Lactic acid is produced in large quantities as a result of glycolysis, which provides the majority of ATP to cells under normal physiological conditions. However, accumulation of lactic acid leads to a decrease in intracellular pH and, thus, to a cessation of glycolysis. In order for glycolysis to continue at a high rate, lactic acid must be transported out of the cell. This transport process is carried out by a family of monocarboxylate transporters (MCTs), which function as proton symports and are stereoselective for L-lactate. MCT13 (Monocarboxylate transporter 13), also known as SLC16A13 (Solute carrier family 16 member 13), is a 426 amino acid multi-pass membrane protein that belongs to the MCT transport family. Functioning as a proton-linked monocarboxylate transporter, MCT13 catalyzes the rapid transports of molecules, such as lactate, across the plasma membrane.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SLC16A13
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene SLC16A13
Gene Accession No. Q66HE2, Q7RTY0, Q8CE94
Gene Alias 1700007D07Rik; MCT 13; MCT13; monocarboxylate transporter; Monocarboxylate transporter 13; monocarboxylic acid transporter 13; MOT13; Slc16a13; solute carrier family 16 (monocarboxylic acid transporters), member 13; solute carrier family 16 member 13; solute carrier family 16, member 13; solute carrier family 16, member 13 (monocarboxylic acid transporter 13)
Gene Symbols SLC16A13
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids 381-426 of Human SLC16A13.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 201232, 287451, 69309
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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