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Invitrogen™ SLC25A36 Polyclonal Antibody
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Catalog No. PIPA5113281
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100 μg
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PIPA5113281 100 μg
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Catalog No. PIPA5113281 Supplier Invitrogen™ Supplier No. PA5113281
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Rabbit Polyclonal Antibody

SLC25A36 Polyclonal Antibody for Western Blot, ICC/IF, IHC (P), ELISA

The SLC25A36 gene is part of the solute carrier family 25 (SLC25), which encodes mitochondrial transport proteins. SLC25A36 specifically functions as a transporter of pyrimidine nucleotides, including deoxynucleotide triphosphates, across the inner mitochondrial membrane. This transport is essential for maintaining mitochondrial DNA synthesis and repair, as well as for the proper functioning of mitochondrial ribonucleotide reductase. The SLC25A36 protein exhibits a characteristic transmembrane structure with six transmembrane helices and a central substrate-binding site. It operates via a mechanism involving substrate binding, conformational changes, and alternating access to the substrate-binding site from either side of the membrane. Dysregulation or mutations in SLC25A36 can lead to mitochondrial dysfunction and are associated with various metabolic disorders.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SLC25A36
Applications ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 3.3 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
Gene SLC25A36
Gene Accession No. Q96CQ1
Gene Alias C330005L02Rik; PNC2; Slc25a36; solute carrier family 25 (pyrimidine nucleotide carrier ), member 36; solute carrier family 25 (pyrimidine nucleotide carrier), member 36; solute carrier family 25 member 36; solute carrier family 25, member 36
Gene Symbols SLC25A36
Host Species Rabbit
Immunogen Recombinant Human Solute carrier family 25 member 36 protein (58-110AA).
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 55186
Target Species Human
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG
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