Invitrogen™ SLC25A36 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5113281

Catalog No. PIPA5113281

Description

SLC25A36 Polyclonal Antibody for Western Blot, ICC/IF, IHC (P), ELISA

The SLC25A36 gene is part of the solute carrier family 25 (SLC25), which encodes mitochondrial transport proteins. SLC25A36 specifically functions as a transporter of pyrimidine nucleotides, including deoxynucleotide triphosphates, across the inner mitochondrial membrane. This transport is essential for maintaining mitochondrial DNA synthesis and repair, as well as for the proper functioning of mitochondrial ribonucleotide reductase. The SLC25A36 protein exhibits a characteristic transmembrane structure with six transmembrane helices and a central substrate-binding site. It operates via a mechanism involving substrate binding, conformational changes, and alternating access to the substrate-binding site from either side of the membrane. Dysregulation or mutations in SLC25A36 can lead to mitochondrial dysfunction and are associated with various metabolic disorders.

Specifications

• Antigen: SLC25A36
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLC25A36
• Gene Alias: C330005L02Rik; PNC2; Slc25a36; solute carrier family 25 (pyrimidine nucleotide carrier ), member 36; solute carrier family 25 (pyrimidine nucleotide carrier), member 36; solute carrier family 25 member 36; solute carrier family 25, member 36
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 55186
• Content And Storage: -20°C or -80°C if preferred
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 3.3 mg/mL
• Formulation: PBS with 50% glycerol and 0.03% ProClin 300; pH 7.4
• Gene Accession No.: Q96CQ1
• Gene Symbols: SLC25A36
• Immunogen: Recombinant Human Solute carrier family 25 member 36 protein (58-110AA).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG