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Invitrogen™ SLC39A4 Polyclonal Antibody
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Catalog No. PIPA547915
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100 μg
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Catalog No. Quantity
PIPA547915 100 μg
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Catalog No. PIPA547915 Supplier Invitrogen™ Supplier No. PA547915
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Description

Goat Polyclonal Antibody

Reconstitute in sterile PBS to a final concentration of 0.2 mg/mL.

The zinc transporter ZIP4, also known as SLC39A4, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP4 was initially identified as zinc-uptake transporter in the intestine and as a candidate gene for acrodermatitis enteropathica (AE), a rare inherited defect in the absorption of dietary zinc. Similar to other ZIP family members, aberrant expression of ZIP4 has been linked to cancer, specifically the progression and aggressiveness of pancreatic cancer. ZIP4 expression has also been shown to be activated in hepatocellular carcinomas, acting to repress apoptosis, enhance cell cycle and increase migration, suggesting ZIP4 may play a role in multiple types of cancers.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SLC39A4
Applications Flow Cytometry, Immunohistochemistry (Frozen), Western Blot
Classification Polyclonal
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 5% trehalose and No Preservative
Gene Slc39a4
Gene Accession No. Q78IQ7
Gene Alias 1600025H15Rik; activated in W/Wv mouse stomach 2; AEZ; AU041686; AWMS2; EMBL:AAI27515.1}; mAWMS2; SLC39A4; slc39a4 {ECO:0000312; solute carrier family 39 (zinc transporter), member 4; solute carrier family 39 member 4; Zinc transporter ZIP4; Zip4; ZIP-4; Zrt- and Irt-like protein 4
Gene Symbols Slc39a4
Host Species Goat
Immunogen Mouse myeloma cell line NS0-derived recombinant mouse SLC39A4 Met1-Tyr337.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 72027
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Lyophilized
Isotype IgG
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