SLC39A5 Monoclonal Antibody (OTI2F2), TrueMAB™, OriGene

Mouse Monoclonal Antibody

Supplier:  OriGene TA810144

Catalog No. 50-168-3220

Description

The zinc transporter ZIP5, also known as SLC39A5, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP5 is closely related to ZIP4, and is found in many of the same tissues, including intestine, pancreas, liver, and kidney, but unlike ZIP4, ZIP5 localizes to the basolateral membrane in kidney cells and its activity is not downregulated by zinc repletion. Recent evidence suggests that ZIP4 and ZIP5 are reciprocally regulated, with translation of ZIP5 mRNA decreasing and ZIP5 protein being rapidly internalized and degraded in response to zinc deficiency.

Specifications

• Antigen: SLC39A5
• Classification: Monoclonal
• Concentration: 1 mg/mL
• Formulation: PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
• Gene Accession No.: Q6ZMH5
• Gene Symbols: SLC39A5
• Immunogen: Human recombit protein fragment corresponding to amino acids 48-178 of human SLC39A5 produced in E.coli.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI2F2
• Conjugate: Unconjugated
• Gene: SLC39A5
• Gene Alias: LZT-Hs7, MYP24, ZIP5
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 283375
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid