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SLC4A4 Recombinant Rabbit Monoclonal Antibody (HL1473), Invitrogen™

Catalog No. PIMA547058
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PIMA547058 100 μL
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Catalog No. PIMA547058 Supplier Thermo Scientific Supplier No. MA547058

Description

Rabbit Recombinant Monoclonal Antibody

Store as concentrated solution. Centrifuge briefly prior to opening vial.

Slc4a4 encodes a sodium bicarbonate cotransporter (NBC) involved in the regulation of bicarbonate secretion and absorption and intracellular pH. Slc4a4 is an electrogenic sodium/bicarbonate cotransporter with a Na(+):HCO3(-) stoichiometry varying from 1:2 to 1:3. Moreover, Slc4a4 may regulate bicarbonate influx/efflux at the basolateral membrane of cells and regulate intracellular pH. Isoform 2: May have a higher activity than isoform 1. Mutations in the Slc4a4 gene are associated with proximal renal tubular acidosis. Multiple transcript variants encoding different isoforms have been found for the Slc4a4 gene. Diseases associated with SLC4A4 include Renal Tubular Acidosis, Proximal, With Ocular Abnormalities and Proximal Renal Tubular Acidosis.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SLC4A4
Applications Western Blot
Classification Monoclonal
Clone HL1473
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative
Gene SLC4A4
Gene Accession No. Q9Y6R1
Gene Alias AI835705; Electrogenic sodium bicarbonate cotransporter 1; electrogenic sodium bicarbonate cotransporter NBCe1 variant D; hhNMC; HNBC 1; HNBC1; KNBC; kNBC 1; kNBC1; Na(+)/HCO3(-) cotransporter; Na+HCO3- cotransporter 4; NBC; NBC 1; NBC 2; NBC1; NBC2; Nbc4; NBCE 1; NBCE1; NBCe1-A; NBC-like protein; OTTHUMP00000160355; OTTHUMP00000218884; OTTHUMP00000218885; pancreas sodium bicarbonate cotransporter; PNBC; Rnbc1; SLC4A4; SLC4A5; sodium bicarbonate cotransporter; sodium bicarbonate cotransporter 1 (sodium bicarbonate cotransporter, kidney; sodium bicarbonate cotransporter, pancreas); solute carrier family 4 (anion exchanger), member 4; solute carrier family 4 (sodium bicarbonate cotransporter), member 4; solute carrier family 4 member 4; solute carrier family 4, member 4; solute carrier family 4, sodium bicarbonate cotransporter, member 4; solute carrier family 4, sodium bicarbonate cotransporter, member 4, brain type; solute carrier family 4, sodium bicarbonate cotransporter, member 5
Gene Symbols SLC4A4
Host Species Rabbit
Immunogen Recombinant protein encompassing a sequence within the N-term region of human SLC4A4. The exact sequence is proprietary.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8671
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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