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Invitrogen™ SLC6A4 Polyclonal Antibody

Catalog No. p-7246561
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500 μL
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PIPA5143522 500 μL
PIPA5143620 100 μL
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Catalog No. PIPA5143522 Supplier Invitrogen™ Supplier No. PA5143522
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Description

Rabbit Polyclonal Antibody

SLC6A4 Polyclonal Antibody for ICC/IF, IHC, mIHC, Western Blot

SERT is an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.
TRUSTED_SUSTAINABILITY

Specifications

Antigen SLC6A4
Applications Immunohistochemistry, Western Blot, Immunocytochemistry, Multiplex Immunohistochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 5mM sodium azide
Gene SLC6A4
Gene Accession No. P31645, P31652, Q60857, Q9XT49
Gene Alias 5 OCD1; 5HT transporter; 5HTT; 5-HTT; 5-HTTLPR; 5-hydroxytryptamine (serotonin) transporter; AI323329; HGNC:11050; hSERT; HTT; Na+/Cl- dependent serotonin transporter; OCD1; OTTHUMP00000163633; serotonin transporter; serotonin transporter 1; Sert; SERT1; Slc6a4; Sodium-dependent serotonin transporter; Sodium-dependent serotonin transporter (5HT transporter) (5HTT); solute carrier family 6 (neurotransmitter transporter serotonin) member 4 (5-hydroxytryptamine (serotonin) transporter); Solute carrier family 6 (neurotransmitter transporter serotonin) member 4 (5-hydroxytryptamine (serotonin) transporter); solute carrier family 6 (neurotransmitter transporter), member 4; solute carrier family 6 (neurotransmitter transporter, serotonin), member 4; solute carrier family 6 member 4; solute carrier family 6, member 4
Gene Symbols SLC6A4
Host Species Rabbit
Immunogen KSITPETPTEIPCGDIRLNAV coupled to KLH.
Purification Method Affinity chromatography
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 15567, 25553, 282365, 6532
Target Species Bovine, Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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