Invitrogen™ SLC7A11 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA116893

Catalog No. PIPA116893

Description

This antibody is not recommended for Immunoprecipitation. Permeablization is recommended prior to performing Flow analysis. Suggested positive control: antigen standard for SLC7A11 (transient overexpression lysate), human stomach protein or stomach tissue lysate.

SLC7A11 (also known as XCT) is a member of a hetromeric, sodium-independent, anionic amino acid transport system. It is highly specific for cysteine and glutamate. SLC7A11 is a mediator of Kaposi sarcoma-associated herpes virus fusion and entry into cells. Increased expression of this protein in primary gliomas is associated with neuronal cell death.

Specifications

• Antigen: SLC7A11
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SLC7A11
• Gene Alias: 9930009M05Rik; AI451155; Amino acid transport system xc-; calcium channel blocker resistance protein CCBR1; CCBR1; cysteine/glutamate transporter; cystine/glutamate transporter; SLC7A11; sodium independent anionic amino acid transport system; solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11; solute carrier family 7 (cationic amino acid transporter, y+ system), member 11; solute carrier family 7 member 11; solute carrier family 7, (cationic amino acid transporter, y+ system) member 11; sut; xCT
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 23657, 26570, 310392
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), In Situ Hybridization (ISH), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: Q9UPY5, Q9WTR6
• Gene Symbols: SLC7A11
• Immunogen: Synthetic peptide made to an N-terminal region of the human xCT protein (between residues 1-50).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov