Invitrogen™ SMAD6 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA141026

Catalog No. 01-676-639

Description

This antibody is predicted to react with equine based on sequence homology. Suggested positive control: HeLa or NIH-3T3 whole cell lysate.

SMAD6 (mothers against decapentaplegic homolog 6) is an antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit selectively BMP (bone morphogenetic proteins) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1. SMAD6 is an inhibitory SMAD (I-SMAD) or antagonistic SMAD.

Specifications

• Antigen: SMAD6
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SMAD6
• Gene Alias: AOVD2; b2b390Clo; HsT17432; MAD homolog 6; mad homolog 7; Madh6; Madh7; Mothers against decapentaplegic homolog 6; mothers against decapentaplegic, drosophila, homolog of, 6; mothers against DPP homolog 6; Msmad6; SMAD; SMAD 6; SMAD family member 6; SMAD SMAD; SMAD, mothers against DPP homolog 6; SMAD6
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 101103068, 17130, 367100, 4091
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 0.02% sodium azide
• Gene Accession No.: O35182, O43541
• Gene Symbols: SMAD6
• Immunogen: Synthetic peptide made to an internal portion of human SMAD6 (between amino acids 30-150) [UniProt O43541].
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Monkey, Sheep
• Product Type: Antibody
• Isotype: IgG