Invitrogen™ SMAD7 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA141506

Catalog No. 01-675-331

Description

This antibody is predicted to react with chimpanzee, canine, pufferfish, xenopus and zebrafish based on sequence homology. Suggested positive control: A549, HepG2.

SMADs are members of the MAD-related family of molecules. MAD-related proteins are a family of intracellular proteins that are essential components in the signaling pathways of the serine/threonine kinase receptors of the transforming growth factor beta superfamily. SMADs can be divided into receptor-regulated SMADs (R-SMADs: SMAD1, SMAD2, SMAD5, SMAD8 and SMAD9), common-mediator SMAD (co-SMAD: SMAD4), and inhibitory SMADs (I-SMADs: SMAD6 and SMAD7). SMAD1, SMAD5, SMAD8 and SMAD9 have high degrees of homology and antibodies are available that recognize sequences common to all of them. SMAD8 and SMAD9 are typically used as alternate names for one another in the literature.

Specifications

• Antigen: SMAD7
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: SMAD7
• Gene Alias: CRCS3; FLJ16482; hSMAD7; MAD (mothers against decapentaplegic, Drosophila) homolog 7; MAD homolog 7; MAD homolog 8; MADH7; MADH8; mothers against decapentaplegic homolog 7; Mothers against decapentaplegic homolog 8; Mothers against decapentaplegic, drosophila, homolog of, 7; mothers against decapentaplegic-like protein 7; mothers against DPP 7; mothers against DPP homolog 7; mothers against DPP homolog 8; SMAD; SMAD 7; SMAD family member 7; SMAD, mothers against DPP homolog 7; Smad7
• Host Species: Rabbit
• Purification Method: Protein G
• Regulatory Status: RUO
• Gene ID (Entrez): 101111414, 17131, 4092
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1.0 mg/mL
• Formulation: PBS with no preservative
• Gene Accession No.: O15105, O35253
• Gene Symbols: SMAD7
• Immunogen: Two peptides made from within amino acids 10 and 50 of human SMAD7.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Sheep
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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