SMARCA2 / BRM Monoclonal Antibody (1H7A10), Active Motif™

Rat Monoclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-199-2870	Active Motif 39806	10 μg
50-199-2869	Active Motif 39805	100 μg

Description

SMARCA2 encodes a protein that is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Two transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism.

Specifications

• Antigen: SMARCA2 / BRM
• Concentration: 1 mg/mL
• Classification: Monoclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
• Gene Alias: 2610209L14Rik; ATP-dependent helicase SMARCA2; BAF190; Baf190b; brahma; BRG1-associated factor 190B; Brm; FLJ36757; global transcription activator homologous sequence; hBRM; hSNF2a; MGC74511; NCBRS; Probable global transcription activator SNF2L2; Protein brahma homolog; SMARCA2; SNF2; SNF2/SWI2-like protein 2; SNF2A; SNF2alpha; SNF2-alpha; SNF2L2; SNF2LA; Sth1p; subunit of the SWI/SNF chromatin remodeling complex; sucrose nonfermenting 2-like protein 2; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a2; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2; SWI2
• Gene Symbols: SMARCA2
• Isotype: IgG2a
• Purification Method: Protein G
• Product Type: Antibody

• Clone: 1H7A10
• Applications: ChIP Assay, Immunocytochemistry, Immunofluorescence
• Conjugate: Unconjugated
• Host Species: Rat
• Target Species: Human, Mouse
• Gene Accession No.: P51531, Q6DIC0
• Gene ID (Entrez): 6595, 67155
• Immunogen: This SMARCA2 / BRM antibody was raised against a recombinant protein corresponding to amino acids 48-214 of mouse BRM.
• Primary or Secondary: Primary
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Gene: SMARCA2