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SMARCC2 / BAF170 Polyclonal Antibody, Active Motif™
SDP

Catalog No. 501993429
Encompass
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50-199-3429 10 μL
50-199-3428 100 μL
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Catalog No. 50-199-3429 Supplier Active Motif Supplier No. 61472
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Description

Rabbit Polyclonal Antibody

Cdc73 is a tumor suppressor probably involved in transcriptional and post-transcriptional control pathways. Cdc73 is part of the PAF1 complex, a five-subunit protein complex composed of Paf1, Cdc73, Leo1, Rtf1 and Ctr9. PAF1 was first purified from yeast in association with RNA polymerase II and is believed to function in transcription elongation. The yeast PAF (yPAF) complex interacts with RNA polymerase II and coordinates the setting of histone marks associated with active transcription. In addition to coordinating events during transcription (initiation, promoter clearance, and elongation), hPAF also coordinates events in RNA quality control. Cdc73 may also be involved in cell cycle progression through the regulation of cyclin D1/PRAD1 expression.

Specifications

Antigen SMARCC2 / BAF170
Applications Immunocytochemistry, Immunofluorescence, Western Blot
Classification Polyclonal
Concentration Lot-Specific
Conjugate Unconjugated
Formulation PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Smarcc2
Gene Accession No. Q6PDG5, Q8TAQ2
Gene Alias 5930405J04Rik; BAF170; BRG1-associated factor 170; chromatin remodeling complex BAF170 subunit; CRACC2; DKFZp313D0632; LOC685179; mammalian chromatin remodeling complex BRG1-associated factor 170; Rsc8; similar to SWI/SNF-related matrix-associated actin-dependent regulator of chromatin c2; SMARCC2; SWI/SNF complex 170 kDa subunit; SWI/SNF complex subunit SMARCC2; SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2; SWI3-like protein
Gene Symbols Smarcc2
Host Species Rabbit
Immunogen This antibody was raised against a peptide within the C-terminal region of mouse SMARCC2 / BAF170.
Purification Method Antigen affinity chromatography
Quantity 10 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 6601, 68094
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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