SMARCC2 / BAF170 Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-199-3429	Active Motif 61472	10 μL
50-199-3428	Active Motif 61471	100 μL

Description

Cdc73 is a tumor suppressor probably involved in transcriptional and post-transcriptional control pathways. Cdc73 is part of the PAF1 complex, a five-subunit protein complex composed of Paf1, Cdc73, Leo1, Rtf1 and Ctr9. PAF1 was first purified from yeast in association with RNA polymerase II and is believed to function in transcription elongation. The yeast PAF (yPAF) complex interacts with RNA polymerase II and coordinates the setting of histone marks associated with active transcription. In addition to coordinating events during transcription (initiation, promoter clearance, and elongation), hPAF also coordinates events in RNA quality control. Cdc73 may also be involved in cell cycle progression through the regulation of cyclin D1/PRAD1 expression.

Specifications

• Antigen: SMARCC2 / BAF170
• Applications: Immunocytochemistry, Immunofluorescence, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: Q6PDG5, Q8TAQ2
• Gene ID (Entrez): 6601, 68094
• Immunogen: This antibody was raised against a peptide within the C-terminal region of mouse SMARCC2 / BAF170.
• Primary or Secondary: Primary
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Gene: Smarcc2

• Concentration: Lot-Specific
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
• Gene Alias: 5930405J04Rik; BAF170; BRG1-associated factor 170; chromatin remodeling complex BAF170 subunit; CRACC2; DKFZp313D0632; LOC685179; mammalian chromatin remodeling complex BRG1-associated factor 170; Rsc8; similar to SWI/SNF-related matrix-associated actin-dependent regulator of chromatin c2; SMARCC2; SWI/SNF complex 170 kDa subunit; SWI/SNF complex subunit SMARCC2; SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 2; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2; SWI3-like protein
• Gene Symbols: Smarcc2
• Isotype: IgG
• Purification Method: Antigen affinity chromatography
• Product Type: Antibody