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SMIFH2, Tocris Bioscience™

Catalog No. 440110
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

FH2 domain inhibitor; prevents actin nucleation

Inhibitor of formin homology 2 (FH2) domains. Prevents formin-mediated actin nucleation and barbed end elongation. Disrupts formin-dependent actin cytoskeletal structures in fission yeast and mammalian NIH 3T3 fibroblasts.

Chemical Identifiers

CAS 340316-62-3
Molecular Formula C15H9BrN2O3S
Molecular Weight (g/mol) 377.212
InChI Key MVFJHEQDISFYIS-XYOKQWHBSA-N
Synonym smifh2, 5e-1-3-bromophenyl-5-furan-2-ylmethylidene-2-sulfanylidene-1,3-diazinane-4,6-dione, smifh-2, 5e-1-3-bromophenyl-5-2-furylmethylene-2-thioxodihydropyrimidine-4,6 1h,5h-dione, 1-3-bromophenyl-5-2-furanylmethylene dihydro-2-thioxo-4,6 1h,5h-pyrimidinedione, 5e-1-3-bromophenyl-5-furan-2-ylmethylidene-2-thioxodihydropyrimidine-4,6 1h,5h-dione
PubChem CID 2258538
IUPAC Name (5E)-1-(3-bromophenyl)-5-(furan-2-ylmethylidene)-2-sulfanylidene-1,3-diazinane-4,6-dione
SMILES C1=CC(=CC(=C1)Br)N2C(=O)C(=CC3=CC=CO3)C(=O)NC2=S

Specifications

Quantity 10 mg
Formula Weight 377.21
Percent Purity >99%
Chemical Name or Material SMIFH2

Safety and Handling

Recommended Storage Store at +4°C
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